ISB ~ Romans 1 v24

God gave them up:God does not hold back his judgment on sin until the end of history but manifests it throughout history as well (Ps 81:12; Acts 7:42). One severe form of judgment is for God to allow recalcitrant sinners to continue in their sin. The graces that would have moved sinners to repentance have been rejected. As a consequence, a dulled moral sense and intense, disordered desires are forms of punishment that such hardened sinners often experience when they revel in their sin. Paul sees this sort of punishment at work among the Gentiles, whom God has handed over to a thousand obscenities and sins against nature (1:26, 28) because they would not acknowledge him or his truth (1:21, 25, 28, 32). In effect, God says to them, “Have it your way.”