ISB ~ Revelation 17 v3

in the Spirit:The Greek expression, which also appears in 1:10 and 21:10, is ambiguous. As rendered in the RSV, it suggests John’s visions are granted by the Holy Spirit and consist of mystical experiences perceived to be in different locations. It could also be translated “in spirit” and refer to John’s interior awareness of the revelations he received.

scarlet beast:Resembles the Satanic dragon in color (red, 12:3) and appearance (seven heads and ten horns, 12:3).