ISB ~ Matthew 20 v22

drink the chalice:An OT metaphor that describes God’s wrath poured upon the wicked (Ps 75:8; Is 51:17; Jer 25:15). Here it denotes Jesus’ Passion endured for sinners (20:28; 26:39; 1 Pet 2:24). James and John are assured (20:23) a share in this Passion, a prediction partially fulfilled with the martyrdom of James in Acts 12:2.